Kim E*, Du H*, Tan Y, Chang Y, Ma M, Brown BL, Sweedler JV and Yu X (2025) Prefrontal cortex astrocytes modulate distinct neuronal populations to control anxiety-like behavior. Nature Communications. 2025 Aug 21;16(1):7819. doi: 10.1038/s41467-025-63131-9. (* Equal contribution)

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Umpierre AD, Li B, Ayasoufi K, Zhao S, Xie M, Thyen G, Hur B, Zheng J, Linag Y, Wu Z, Yu X, Sung J, Johnson AJ, Li Y and Wu LJ (2024) Microglial P2Y6 calcium signaling promotes phagocytosis and shapes neuroimmune responses in epileptogenesis. Neuron. 2024 Apr 10:S0896-6273(24)00195-8.

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Yook Y, Lee KY, Kim E, Lizarazo S, Yu X and Tsai NP (2024) Hyperfunction of post-synaptic density protein 95 promotes seizure response in early-stage Aβ pathology. EMBO reports. 2024 Mar;25(3):1233-1255.

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Iyer M, Kantarci H, Cooper MH, Ambiel N, Novak SW, Andrade LR, Lam M, Jones G, Munch AE, Yu X, Khakh BS, Manor U and Zuchero JB (2024) Oligodendrocyte calcium signaling promotes actin-dependent myelin sheath extension. Nature Communications. 2024 Jan;15(265).

 

Phi NT, Yu X and Hong W (2023) Control of social hierarchy beyond neurons. Nature Neuroscience. 2023 Sep;26(9):1485-1486.

 

Institoris A, Vandal M, Peringod G, Catalano C, Tran CH, Yu X, Visser F, Breiteneder C, Molina L, Khakh BS, Nguyen MD, Thompson RJ and Gordon GR (2022) Astrocytes amplify neurovascular coupling to sustained activation of neocortex in awake mice. Nature Communications. 2022 Dec 22;13(1):7872.

 

Endo F, Kasai A, Soto JS, Yu X, Qu Z, Hashimoto H, Gradinaru V, Kawaguchi R, Khakh BS (2022) Molecular basis of astrocyte diversity and morphology across the CNS in health and disease. Science. 2022 Nov 4;378(6619):eadc9020. 

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Cho FS, Vainchtein ID, Voskobiynyk Y, Morningstar AR, Aparicio F, Higashikubo B, Ciesielska A, Broekaart DWM, Anink JJ, van Vliet EA, Yu X, Khakh BS, Aronica E, Molofsky AV and Paz JT (2022) Enhancing GAT-3 in thalamic astrocytes promotes resilience to brain injury. Science Translational Medicine. 2022 Jul 6;14(652):eabj4310. doi: 10.1126/scitranslmed.abj4310. Epub 2022 Jul 6.

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Yu X (2022) Hippocampal astrocytes represent navigation space. PLoS Biology. 20(3): e3001568. https://doi.org/10.1371/journal. pbio.3001568.

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Yu X and Khakh BS (2022) SnapShot: Astrocyte interactions. Cell. 2022 Jan 6; 185(1): 220-220.E1. doi: https://doi.org/10.1016/j.cell.2021.09.029

 

Nagai J, Bellafard A, Qu Z, Yu X, Ollivier M, Gangwani MR, Diaz-Castro B, Coppola G, Schumacher SM, Golshani P, Gradinaru V, Khakh BS (2021) Specific and behaviorally consequential astrocyte Gq GPCR signaling attenuation in vivo with iβARK. Neuron. 2021 Jul 21;109(14):2256-2274.e9. doi: 10.1016/j.neuron.2021.05.023.

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Yu X, Moye SL and Khakh BS (2021) Local and CNS-wide astrocyte intracellular calcium signalling attenuation in vivo with CalExflox mice. Journal of Neuroscience. 26 April 2021, JN-RM-0085-21; DOI: https://doi.org/10.1523/JNEUROSCI.0085-21.2021

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Nagai J*, Yu X*, Papouin T, Cheong E, Freeman MR, Monk KR, Hastings MH, Haydon PG, Rowitch D, Shaham S, Khakh BS (2021) Behaviorally consequential astrocytic regulation of neural circuits. Neuron. 2021 Feb 17;109(4):576-596. (* Equal contribution)

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Yu X*, Nagai J*, Marti-Solano M, Soto JS, Coppola G, Babu MM and Khakh BS (2020) Context-specific striatal astrocyte molecular responses are phenotypically exploitable. Neuron. 2020 Oct 9:S0896-6273(20)30745-5. (* Equal contribution)

 

Yu X*, Nagai J* and Khakh BS (2020) Improved tools to study astrocytes. Nature Reviews Neuroscience. 2020 Mar;21(3):121-138. (* Equal contribution)

 

Diaz-Castro B, Gangwani MR. Yu X, Coppola G and Khakh BS (2019) Astrocyte molecular signatures in Huntington’s disease. Science Translational Medicine. 2019 Oct 16;11(514).

 

Yu X, Taylor AMW, Nagai J, Golshani P, Evans CJ, Coppola G and Khakh BS (2018) Reducing astrocyte calcium signaling in vivo alters striatal microcircuits and causes repetitive behavior. Neuron. 99(6):1170-1187

 

Chai H, Diaz-Castro B, Shigetomi E, Monte E, Octeau JC, Yu X, Cohn W, Rajendran PS, Vondriska TM, Whitelegge JP, Coppola G and Khakh BS (2017) Neural circuit-specialized astrocytes: transcriptomic, proteomic, morphological, and functional evidence. Neuron. 95(3):531-549.

 

Tjia M, Yu X, Jammu LS, Lu J and Zuo Y (2017) Pyramidal neurons in different cortical layers exhibit distinct dynamics and plasticity of apical dendritic spines. Frontier in Neural Circuits. 11:43.

 

Hodges JL*, Yu X*, Gilmore A, Bennett H, Tjia M, Perna JF, Chen CC, Li X, Lu J and Zuo Y (2017) Astrocytic contributions to synaptic and learning abnormalities in a mouse model of Fragile X Syndrome. Biological Psychiatry. 82(2): 139-149. (* Equal contribution)

 

Zemmar A, Weinmann O, Kellner Y, Yu X, Vicente R, Gullo M, Kasper H, Lussi K, Ristic Z, Luft AR, Rioult-Pedotti M, Zuo Y, Zagrebelsky M and Schwab ME (2014) Neutralization of Nogo-A enhances synaptic plasticity in the rodent motor cortex and improves motor learning in vivo. Journal of Neuroscience. 25;34(26):8685-98.

 

Yu X, Zuo Y (2014) Two-photon in vivo imaging of dendritic spines in the mouse cortex using a thinned-skull preparation. Journal of Visualized Experiments: JoVE. 2014 May 12;(87)

 

Yu X, Wang G, Gilmore A, Yee AX, Li X, Xu T, Smith SJ, Chen L and Zuo Y (2013) Accelerated experience-dependent pruning of cortical synapses in ephrin-A2 knockout mice. Neuron. 80(1):64-71.

 

Zuo Y, Yu X, Tennant K and Jones T (2013) In vivo imaging of synapse plasticity in the mouse motor cortex. Methods in Molecular Biology. 1010:45-57.

 

Fu M, Yu X, Lu J and Zuo Y (2012) Repetitive motor learning induces coordinated formation of clustered dendritic spines in vivo. Nature. 483(7387):92-5.

 

Yu X, Zuo Y (2011) Spine plasticity in the motor cortex. Current Opinion in Neurobiology. 21(1):169-74.

 

Xu T*, Yu X*, Perlik A, Tobin W, Zweig J and Zuo Y (2009) Rapid formation and selective stabilization of synapses for enduring motor memories. Nature. 462(7275):915-9. (* Equal contribution)

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